Although long overlooked, exosomes are rapidly gaining momentum as anovel strategy for accessing the therapeutic effects of stem cells without the risks and difficulties of administering the cells to patients.
Although exosomes were discovered more than 30 years ago, it was not until recently that the scientific community began to give credit to exosomes for a range of promising traits. Ten years ago in 2006, there were only 76 articles published about exosomes onPubMed.gov. Today, there are more than 4,400 articles published about exosomes onPubMed.gov, of which approximately 25% were released in the past year.
When exosome publications are analyzed, U.S. authors published approximately 40% of the articles and Chinese authors take second place. When the term “exosome” is searched within the scientific literature, Dr. Susanne Gabrielsson from the Karolinska Institutet in Sweden is the leading author, with 37 articles.
When the term “extracellular vesicles” is searched, Unicyte AG, a regenerative medicine unit of Fresenius Medical Care, takes the lead. Headquartered in Switzerland, the company has published more than 100 papers on exosomes and extracellular vesicles in combination with Prof. Giovanni Camussi.
On the venture capital front, there has also been a great deal of market activity. In January 2016, Exosome Diagnostics closed $60 million in Series B financing, which it followed in July 2017 with $30 million in Series C financing. Similarly, Codiak Biosciences was launched in 2016 when the MD Anderson Cancer Center joined two venture capital firms to form the company with more than $80 million in series A and B financing. On November 29, 2017, Codiak BioSciences added another $76.5 million in Series C financing. In May 2017, ExCoBio Inc. raised US $11 million in a Series A funding round.
Companies leading the charge in the area of exosome therapeutics include Anjarium Biosciences, Capricor Therapeutics, Codiak Biosciences, Creative Medical Technology Holdings, Everkine Corporation, Evox Therapeutics, Exogenus Therapeutics, Kimera Labs, ReNeuron, and Unicyte AG, a subsidiary of Fresenius Medical Care.
Numerous life science companies have also launched tools and systems to support exosome research, including Beckman Coulter, Exiqon, System Biosciences (SBI), Lonza, Thermo Fisher, Qiagen, ZenBio, and more. In particular, Lonza made aggressive investments in the sector through its May 2017 acquisition of HansaBioMed Life Sciences and investment into Exosomics.
Similarly, techniques for large-scale clinical-grade manufacture of stem cell exosomes is becoming a focal point within the industry, as highlighted by a recent partnership between RoosterBio and Exopharm, as well as Lonza’s strategic acquisitions. VivaZome Therapeutics was also awarded a grant of $2.18M by the Australian government to support an exosome manufacturing project.
To characterize this rapidly forming marketplace, we have released a 134-page market report that explores growing demand for exosome therapeutics, diagnostics, research tools, consumer care products, and manufacturing technologies. It also reveals trend rate data for exosome patents, grants, scientific publications, and clinical trials, and present social analytics from Google Trends and Google Adwords.
Claim it to:
1. Identify the five market segments that compose the industry
2. Reveal the market players competing in each niche
3. Identify opportunities for exosome product development
4. Access market size determinations & projections through 2022
According to Cade Hilbarth at bioinformant.com
(The World’s Largest Stem Cell Industry Blog)